Abram Hoffer, MD, Ph.D. (1917-2009), a founder of Orthomolecular Medicine was a world-renowned Canadian doctor and biochemist that treated over five thousand patients with mental disorders (including schizophrenia, drug/alcohol addiction, and psychosis) through better nutrition, micronutrients, and megavitamin therapy. Dr. Abram Hoffer, a pioneer of holistic nutritional/vitamin therapy, died in May 2009 at the age of 91. For over 50 years, Dr. Abram Hoffer personally took 4,500 mg (4.5 grams) of Niacin (Vitamin B-3) along with other supplements. Dr. Abram Hoffer was a prolific researcher and writer, wrote over 30 books and 600 peer-reviewed medical journal articles (most of which were ignored by mainstream medicine), and was productive until 2 weeks prior to his death (age 91).